1.Basic Information:
Product name | 5-Methoxytryptamine hydrochloride |
Appearance | White crystal powder |
CAS No | 66-83-1 |
Molecular formula | C11H15ClN2O |
Molecular weight | 226.703 |
Boiling point | 380℃ at 760 mmHg |
Melting point | 246 °C |
Flash point | 183.6°C |
Density | 1.171 g/cm3 |
Storage | 2-8°C, sealed away from light |
Application | Raw materials and intermediates, intermediates of "melatonin". |
2.COA:
CERTIFICATE OF ANALYSIS
Product name | 5-Methoxytryptamine hydrochloride | Country of Origin | China |
Batch Size | 500KG | Batch Number | 20220508 |
Manufacture Date | May 8, 2022 | Expiry Date | May 7, 2023 |
ITEM | STANDARD | RESULT |
Identification | Positive reaction | Conform |
Loss on drying | 0.5% MAX | 0.04% |
Sulphated Ash | 0.5% MAX | 0.06% |
Color test | 0.5% Reference solution | conform |
Heavy metal | 20PPM MAX | conform |
Assay(HPLC) | 98.0% MIN | 99.12% |
Conclusion: Comply with the requirements of enterprise standard.
3. Function:
5-Methoxytryptamine is a tryptamine derivative that is closely related to the neurotransmitters melatonin and serotonin. It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors, but has no affinity for the 5-HT3 receptor. It is a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors. 5-Methoxytryptamine hydrochloride has similar efficacy to 5-methoxytryptamine. However, compared with 5-methoxytryptamine, 5-methoxytryptamine hydrochloride has stronger stability and better water solubility.
4.Application:
The protective effect of 5-methoxytryptamine, a metabolite of melatonin, in human keratinocytes against ultraviolet B (UVB) has been investigated. 5-Methoxytryptamine as an agonist has been used in pharmacological studies of serotonin-1 receptors.
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