Home> Products> Active Pharmaceutical Ingredients> 5 Methoxytryptamine Hydrochloride Powder 343-94-2
5 Methoxytryptamine Hydrochloride Powder 343-94-2
5 Methoxytryptamine Hydrochloride Powder 343-94-2
5 Methoxytryptamine Hydrochloride Powder 343-94-2

5 Methoxytryptamine Hydrochloride Powder 343-94-2

$20-25 /Kilogram

Payment Type:T/T
Incoterm:CIF,CPT,DDP,FOB,DAF,CFR,DES,EXW,FAS,FCA,CIP,DEQ,DDU,Express Delivery
Min. Order:1 Kilogram
Transportation:Ocean,Land,Air,Express,Others
Port:Shanghai,Guangzhou,Tianjin
Product Attributes

BrandYouth

Place Of OriginChina

Application FieldDetergent Raw Materials, Oral Care Chemicals

AppearanceWhite crystal powder

Product Name5-Methoxytryptamine hydrochloride

Molecular Weight226.703

Boiling Point246 °C

Molecular FormulaC11H15ClN2O

CAS No66-83-1

Packaging & Delivery
Selling Units : Kilogram
Package Type : 25kg/ Aluminum foil bag;
Product Description


1.Basic Information:

Product name

5-Methoxytryptamine hydrochloride

Appearance

White crystal powder

CAS No

66-83-1

Molecular formula

C11H15ClN2O

Molecular weight

226.703

Boiling point

380 at 760 mmHg

Melting point

246 °C

Flash point

183.6°C

Density

1.171 g/cm3

Storage

2-8°C, sealed away from light

Application

Raw materials and intermediates, intermediates of "melatonin".

 

 

 

2.COA

  CERTIFICATE OF ANALYSIS                                                  

Product name

5-Methoxytryptamine hydrochloride

Country of Origin

China

Batch Size

500KG

Batch Number

20220508

Manufacture Date

May 8, 2022

Expiry Date

May 7, 2023

 

ITEM

STANDARD

RESULT

Identification

Positive reaction

Conform

Loss on drying

0.5% MAX

0.04%

Sulphated Ash

0.5% MAX

0.06%

Color test

0.5% Reference solution

conform

Heavy metal

20PPM MAX

conform

Assay(HPLC)

98.0% MIN

99.12%

Conclusion: Comply with the requirements of enterprise standard.

 

 


3. Function:

5-Methoxytryptamine is a tryptamine derivative that is closely related to the neurotransmitters melatonin and serotonin. It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors, but has no affinity for the 5-HT3 receptor. It is a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors. 5-Methoxytryptamine hydrochloride has similar efficacy to 5-methoxytryptamine. However, compared with 5-methoxytryptamine, 5-methoxytryptamine hydrochloride has stronger stability and better water solubility.

 

4.Application:

The protective effect of 5-methoxytryptamine, a metabolite of melatonin, in human keratinocytes against ultraviolet B (UVB) has been investigated. 5-Methoxytryptamine as an agonist has been used in pharmacological studies of serotonin-1 receptors.

Reactants for the preparation of:

1. Carboline disaccharide domain of shishijimicin A

2. Melatonin analogs for lowering intraocular pressure

3.5-HT4 receptor ligands

4. Inhibitors of sortase A and isocitrate lyase

5. Therapeutic agents for the treatment of ischemia/reperfusion (I/R) injury

6. Aurora and epidermal growth factor receptor kinase inhibitors

7. Agents for the treatment of human papillomavirus infection

8. Manzamine analogs are used to control neuroinflammation and brain infections

9. Inhibitors of pro-inflammatory cytokines

10. Tacrine-melatonin hybrids as multifunctional drugs for Alzheimer's disease





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