Improving Liver Function Silymarin Milk Thistle Extract Powder
1.Introduction of Milk Thistle Extract Powder:
Milk Thistle Extract
Silymarin, a natural active substance extracted from the dried fruit of silymarin, is the most effective flavonoid for liver disease found in the world.
Water-soluble silymarin is a silymarin product synthesized on the basis of silymarin and meglumine. Water-soluble silymarin solves the problem that silymarin is insoluble in water and affects bioavailability. It can be quickly dissolved in water and is easier to be absorbed and utilized.
Silybin is the main active ingredient in silymarin, which can protect liver, improve liver function and enhance liver cell regeneration. It has good curative effect on acute and chronic hepatitis, liver cirrhosis and metabolic toxic liver injury. The higher the silybin content, the higher the protective dry activity.
2.Basic Information
Product Name | Milk Thistle Extract |
Specification | 40%, water soluble, light brown 80% UV, insoluble in water, yellow 98% HPLC, insoluble in water, off-white 70% UV, organic, insoluble in water |
Other Name | silybine; Silibinin; silliver; SILYBININ |
Property and Flavor | Bitter, cool |
Function | Clearing heat and dampness; Dredge the liver and benefit the gall. |
CAS | 65666-07-1 |
Test Method | HPLC, UV |
Active Ingredient | Silymarin, silybin |
Packaging | 25kg/cardboard drum; 1 kg/aluminum foil bag; Or according to customer demand packaging. |
3.COA
tems | Standards | Results |
Physical Analysis | | |
Description | Brown Yellow Powder | Complies |
Assay | Silymarin 80% (UV) | 81.13% |
Mesh Size | 100 % pass 80 mesh | Complies |
Ash | ≤ 5.0% | 2.85% |
Loss on Drying | ≤ 5.0% | 2.85% |
Chemical Analysis | | |
Heavy Metal | ≤ 10.0 mg/kg | Complies |
Pb | ≤ 2.0 mg/kg | Complies |
As | ≤ 1.0 mg/kg | Complies |
Hg | ≤ 0.1 mg/kg | Complies |
Microbiological Analysis | | |
Residue of Pesticide | Negative | Negative |
Total Plate Count | ≤ 1000cfu/g | Complies |
Yeast&Mold | ≤ 100cfu/g | Complies |
E.coil | Negative | Negative |
Salmonella | Negative | Negative |
4.Specification
| Specification & Test Method | |
Silymarin extracted by acetone | UV80% UV80%, silybin+Isosilybin30% UV80%, silybin30% UV85%, Silybin35% HPLC45% HPLC50% HPLC55% HPLC60% | Insoluble in water, soluble in acetone |
Silymarin extracted by ethano | UV80% UV80%, silybin+Isosilybin30% UV80%, silybin30% UV85%, Silybin35% HPLC45% HPLC50% HPLC55% HPLC60% | Insoluble in water, soluble in ethanol |
Silymarin extracted by ethyl acetate | UV80% UV80%, silybin+Isosilybin30% UV80%, silybin30% UV85%, Silybin35% HPLC45% HPLC50% HPLC55% HPLC60% | Insoluble in water, soluble in ethyl acetate |
Water Soluble Silymarin | UV20% UV40% UV45% | Soluble in water and ethanol |
Silybin | Silybin 80% Silybin 90% Silybin 95% Silybin 98% HPLC60%-90% | Insoluble in water, soluble in acetone |
Organic silymarin | 70%UV | Insoluble in water, soluble in ethanol |
5. Function
1. Get rid of the reactive oxygen: Directly getting rid of the reactive oxyge, resist lipid peroxidation, and maintain the fluidity of cell membranes;
2. Liver-protective effect: Silymarin has a protective effect on liver damage caused by carbon tetrachloride, galactosamine, alcohols and other liver toxins;
3. Anti-tumor effect: A variety of reactive oxygen species can oxidize guanine to form 8-amino-guanine, which can cause DNA damage and then cause tumor. Antioxidant, especially free radical scavenger, can prevent this process from happening ;
4. Anti-cardiovascular disease effect ;
5. Protective effect of cerebral ischemia injury: silymarin can improve the antioxidant capacity of the body, and has a significant protective effect on cerebral ischemia injury.;
6.Application
1. Widely used in the production and processing of functional food, beverage and health care products;
2. Silybin is the main component of synthetic silybin derivatives.