3. Function:
N-Acetyl-L-cysteine (NAC), which exerts a strong mucolytic effect by breaking down mucin complexes, nucleic acids, and changing purulent components of sputum and other mucus and mucus secretions from viscous to thin. In addition, it exerts a direct antioxidant effect through a free sulfhydryl group (nucleophilic -SH) that interacts directly with an electrophile oxidation group.
Bioreagent, API, the sulfhydryl group (-SH) contained within the molecule breaks the disulfide chain (-S-S) linking the peptide chain of mucin in mucus sputum. The mucin becomes small molecules of peptide chains and reduces the stickiness of sputum; it also breaks DNA fibers in purulent sputum, so it can dissolve not only white mucous sputum but also purulent sputum.
The molecular structure of this product makes it easy to pass through the cell membrane. In the cell, the product deacetylates to form L-cysteine, an essential amino acid for the synthesis of glutathione (GSH).
4. Application:
Used in biochemical studies and as a mucolytic drug. It is used for respiratory obstruction caused by large amounts of mucous sputum obstruction. Also used for detoxification of acetaminophen poisoning.
5. COA
Certificate of Analysis
| ProductName:N-Acetyl-L-Cysteine | Quantity:5000kgs | Batch No: 20220825 |
| Producing date: 20220825 | Sampling date: 20220828 | Send out date: 20220828 |
| Reference standard: AJI92 | Package: 25kg/drum | Expiry date: 2024.08.24 |
| Item | Specifications | Test Results |
| Specific optical rotation[a]D20° | +21.3o ~ +27.0 o | +23.6o |
| State of solution (Transmittance) | Not less than 98.0% | 98.6% |
| Assay | 98.5%~101.0% | 99.10% |
| Heavy metals(Pb) | Not more than 10ppm | 2ppm |
| Chloride (Cl) | Not more than 0.04% | 0.030% |
| Ammonium (NH4) | Not more than 0.02% | 0.010% |
| Sulfate (SO4) | Not more than 0.030% | 0.012% |
| Iron (Fe) | Not more than 20ppm | 2ppm |
| Arsenic (As2O3) | Not more than 1ppm | 0.5ppm |
| Loss on drying | Not more than 3% | 2.9% |
| Residue on ignition | Not more than 0.2% | 0.12% |
| PH | 2.0~2.8 | 2.5 |
| Melting point | 106°to110° | pass |
| Other amino acids | Chromatographically not detectable | Qualified |
| Conclusion: This product complies with AJI92 standard. |
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